ABSTRACT
<p><b>OBJECTIVE</b>To analyses the clinical application of thoracodorsal artery perforator flaps (TAP).</p><p><b>METHODS</b>We used free or pedicled TAP flaps in 7 patients from Aug 2006 to April 2007, The age ranged from 7 to 42 years old, the perforator arteries was detected and labeled with a hand held Doppler flowmeter, the size of flaps ranged from 6 cm x 9 cm - 12 cm x 16 cm, the flaps designed with perforator artery included, all the flaps are based on the first perforator artery.</p><p><b>RESULTS</b>All the flaps survived well, no complication occurred with lowest donor site morbidity.</p><p><b>CONCLUSIONS</b>The thoracodorsal artery flap with latissimus dorsal muscle saved is a thin and reliable flaps with robust of blood supply, the flap can reduce significantly donor site morbidity and is a good choice for reconstructive surgery.</p>
Subject(s)
Adolescent , Adult , Child , Female , Humans , Male , Young Adult , Back , Plastic Surgery Procedures , Methods , Surgical Flaps , Thoracic Arteries , TransplantationABSTRACT
<p><b>OBJECTIVE</b>To explore a new method to reconstruct the defect of the distal foot.</p><p><b>METHODS</b>A distally based dorsum pedis island flap pedicled with the first dorsal metatarsal artery was designed and transferred to the defect of the distal foot.</p><p><b>RESULTS</b>Five patients were treated with this flap, which ranged from 2 cm x 4 cm to 6 cm x 7 cm in size. Four flaps survived completely, one flap had marginal necrosis and healed after conservative therapy.</p><p><b>CONCLUSIONS</b>The reverse first dorsal metatarsal artery flap, with good blood circulation and easy manipulation, is a good option for the defects of the distal foot.</p>
Subject(s)
Adolescent , Adult , Child , Female , Humans , Male , Middle Aged , Young Adult , Foot Injuries , General Surgery , Metatarsus , Skin Transplantation , Methods , Surgical FlapsABSTRACT
OBJECTIVE@#To explore the microvessel counts and the expressions of interleukin-8 (IL-8), monocyte chemoattractant protein-1 (MCP-1), and macrophage inflammatory protein-1 ( MIP-1) alpha mRNA in the pathological scar tissues.@*METHODS@#Immunohistochemical method of avidin-biotin complex was used for microvessel counts on the routinely formalin-fixed and paraffin-embedded sections of specimens of hypertrophic scars, keloids, normal skin, and surgical scar, and in situ hybridization for the expressions of IL-8, MCP-1, MIP-1alpha mRNA.@*RESULTS@#The microvessel counts as well as the positive rates and the scorings of IL-8, MCP-1, and MIP-1alpha mRNA were significantly higher in pathological scars than those in the normal skin and surgical scar (all P < 0.05). The microvessel counts were significantly higher in the positive cases of IL-8, MCP-1 and MIP-1alpha mRNA than those in the negative ones (P < 0.05). The close positive correlations were found among the microvessel counts and the expressive scorings of 3 factors (P < 0.05). The close positive correlations were also found among the expressive scorings of IL-8, MCP-1, and MIP-1alpha mRNA in pathological scars. Microvessel counts were significantly higher in hypertrophic scars with the course less than 1 year than those with the course more than 1 year.@*CONCLUSION@#IL-8, MCP-1 and MIP-1alpha play important roles in promoting the neovascularization of pathological scars.